IgA Antibodies & Mucosal Immunity
Question: Why is IgA a preferred isotype for targeting pathogens at mucosal surfaces? Answer: IgA is the predominant antibody class found in external secretions, such as saliva, tears, and the gastrointestinal tract, where it exists primarily as a dimeric molecule linked by a J-chain. This structural adaptation makes specialized IgA antibodies and reagents indispensable for neutralizing viruses...
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