Deciphering the Glycan-Code: Optimizing Antibody Effector Functions for Next-Generation Biotherapeutics
In the rapidly evolving landscape of biopharmaceuticals, monoclonal antibodies (mAbs) have emerged as the cornerstone of targeted therapy for oncology and immunology. However, the clinical success of a therapeutic antibody is not solely determined by its ability to bind to a target. The real efficacy often lies in the Fc region's ability to engage the host's immune system. Understanding and...
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