Thomas Schmitt

Thomas Schmitt added blog Health
2026-08-13 09:20:24 -

Characterized Peritoneal Fibrosis Models for Renal Research
Peritoneal dialysis (PD) is one of the most commonly used dialysis methods, playing a vital role in maintaining the quality of life of patients with end-stage renal disease. However, long-term PD treatment can adversely affect the structure and function of peritoneal tissue. This can lead to failure of peritoneal ultrafiltration, resulting in dialysis failure and necessitating discontinuation...

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Thomas Schmitt added blog Health
2026-08-13 09:03:56 -

Comprehensive Lipidomics Services to Accelerate Biomarker Discovery and Disease Research
Lipids play a vital role in biological membranes. They provide a barrier for almost all cellular structures and act as dynamic building blocks, enabling certain membrane proteins to function efficiently and facilitating signal transduction. In addition to their involvement in metabolism and energy conversion, lipids are also involved in various developmental processes, such as cell growth and...

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Thomas Schmitt added blog Health
2026-07-20 03:51:45 -

Hantavirus Research Reagents and Products to Accelerate Global Diagnostic and Vaccine Research
Hantaviruses are emerging zoonotic pathogens that belong to the Bunyaviridae family. The US Centers for Disease Control and Prevention (CDC) classifies them as Category A pathogens. They pose a serious threat to human health as their infection can lead to haemorrhagic fever with renal syndrome (HFRS) or hantavirus cardiopulmonary syndrome (HCPS), both of which are highly fatal. These pathogens...

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Thomas Schmitt added blog Health
2026-06-24 05:41:57 -

Advanced MERS-CoV Animal Models to Accelerate Coronavirus Vaccine and Drug Development
MERS-CoV is an emerging zoonotic virus that is considered to be one of the major public health threats. Since 2012, there have been consistent monthly cases of MERS-CoV causing severe respiratory illness, resulting in the death of approximately 35% of confirmed patients. It is believed that the virus is transmitted from camels in Middle Eastern countries through contact between humans and...

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Thomas Schmitt added blog Health
2026-06-22 06:43:24 -

SpeX™ Rainbow Trout Hepatocytes to Advance Toxicology and Metabolism Research
Metabolic stability is a key factor to consider in the early stages of drug discovery. Even if a compound possesses promising pharmacological properties, it will never become a drug if it has poor metabolic stability. For instance, if a drug is rapidly metabolized in vivo, exposure levels may be insufficient, which could lead to the formation of toxic, inactive or active metabolites....

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Thomas Schmitt added blog Health
2026-05-28 02:51:42 -

Flow Cytometry Antibodies to Advance Non-Human Primate Research
Although non-human primates account for only a small proportion of the animals used in biomedical research, they remain important research models due to their high degree of similarity to humans in terms of genetic makeup, anatomy, physiology and behaviour. Key medical advances have been driven by research conducted using non-human primates, primarily monkeys, saving or improving the lives of...

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Thomas Schmitt added blog Health
2026-04-20 08:35:10 -

Antiviral Portfolio with Enhanced Influenza A Virus Mouse Model Services for Preclinical Research
The influenza virus belongs to the family Orthomyxoviridae and has three types: A, B, and C. Infection by the influenza A virus is the most common and severe and is generally found in humans. It spreads rapidly, affecting human populations across large geographical regions within a short period of time, with varying degrees of pathology ranging from mild to severe. Wild aquatic birds and other...

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Thomas Schmitt added blog Health
2026-04-15 07:22:07 -

SpeX™ Earthworm Microsomes for Drug Metabolism and Environmental Toxicology Research
Earthworms are a valuable, multifunctional resource in drug development. They have evolved sophisticated defense mechanisms against microbial infections, and the bioactive agents in earthworm extracts (EEs) demonstrate potent antibacterial, antifungal, and antiviral properties in both in vitro and in vivo studies. EE alleviates inflammation triggered by infections and effectively mitigates...

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Thomas Schmitt updated the profile picture
2026-04-15 07:19:27 -

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